DIABETES BEFORE AND AFTER INSULIN

Diabetes before and after insulin.

FiPTy YEARS AGO, a research project was under way at the University of Toronto that would soon revolutionize the treatment of diabetes. The first public announcement was made on 14 November 1921. The reports that an extract of pancreas had demonstrated life-saving effects were at first received with scepticism, incredulity, and faint hope. But soon the miracle of insulin was everywhere acclaimed.

Leptin before and after insulin therapy in children with new-onset type 1 diabetes.

Serum leptin levels reflect the amount of body fat. However, several reports suggest that insulin may also regulate serum leptin levels. This study was aimed at testing whether leptin levels are low in newly diagnosed patients with type 1 diabetes and increase after institution of insulin therapy. Nineteen children with new-onset type 1 diabetes were studied. Serum leptin levels were measured a...

Annual Medical Costs of Swedish Patients with Type 2 Diabetes Before and After Insulin Initiation

INTRODUCTION Although insulin is one of the most effective interventions for the treatment of type 2 diabetes, its disadvantages incur substantial medical cost. This study was designed to evaluate the medical costs of Swedish type 2 diabetic patients initiating insulin on top of metformin and/or sulfonylurea (SU), and to evaluate if costs before and after insulin initiation differ for patients ...

Insulin binding to erythrocytes before and after changing from porcine to biosynthetic human insulin in children with type-I diabetes.

The binding of [125I]insulin to isolated erythrocytes from diabetic children (n = 27) before (group a) as well as one and five months after changing from porcine to biosynthetic human insulin (groups b and c) was investigated. An analysis of variance of the binding parameters, determined by a nonlinear regression procedure, yielded statistically significant differences between the receptor affi...

Before After Before After